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According to Elsevier, ClinicalKey contains professional practice guidelines published in journals available from this publishing platform. This means many US-based guidelines are available. In addition, CK includes guidelines from the National Institute for Health and Care Excellence (NICE)."
Clinical Trails originate with the ClinicalTrials.Gov database, hosted by the National Institutes of Health.
The National Institute for Health and Care Excellence (NICE)
NICE's role is to improve outcomes for people using the NHS and other public health and social care services. NICE guidelines make evidence-based recommendations on a wide range of topics, from preventing and managing specific conditions to planning broader services and interventions to improve the health of communities in England.
ClinicalTrials.gov is a registry and results database of publicly and privately supported clinical studies of human participants conducted around the world.