The publisher of UpToDate provides a citation example on its website that doesn't follow AMA guidelines.
DMU Librarians recommend the following citation formatting that relies on elements of AMA citation style, specifically chapter of an edited book, a webpage that changes over time, and an online source without a DOI. DMU Librarians also suggest that citation format should first adhere to requirements set by instructors and/or journal/publisher editorial staff.
Format
Author name. Article/chapter title. In: Deputy editor name, ed. UpToDate. Publisher. Use literature review update. Accessed date. URL
Example
Friedman LS. Approach to the patient with abnormal liver tests. In: Law K, ed. UpToDate. Wolters Kluwer. Updated July, 2024. Accessed August 12, 2024. https://www.uptodate.com/contents/approach-to-the-patient-with-abnormal-liver-tests