First, reflect on what type of information you need. Do you need a bottom line answer to a Who-What-Where-Why kind of question or do you need to know the answer to a complex clinical scenario?
Background questions
Background questions are usually broadly worded, and reflect the need to better understand a problem, need, or condition. For example:
Background questions are often answered from secondary information resources.
Foreground questions:
Foreground questions require specific knowledge and include numerous clinical variables. Foreground questions are also called PICO questions. For example:
If you are asking foreground questions, then you most likely need to look for the evidence in the primary literature, focusing on locating relevant journal articles.
1 Large List of Quotes by W. Edwards Deming « The W. Edwards Deming Institute Blog. (n.d.). Retrieved July 20, 2017, from https://blog.deming.org/w-edwards-deming-quotes/large-list-of-quotes-by-w-edwards-deming/