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Evidence Based Practice: Study Methodology

An Interprofessional Guide

Learn More About the Levels (or Hierarchy) of Evidence

To learn more about levels of evidence and research designs, read How to Read a Paper by Trisha Greenhalgh and watch the video tutorials below.

This video by the Duke University Medical Center Library provides a great overview of all the studies in the EBP levels of Evidence Pyramid.

Learn About Experimental Research Methods

Dr. Terry Shaneyfelt demonstrates how to use data from a study to calculate an individual patients risk of the study outcome. This is important to know how to do because the patients you see in the office or in the hospital are often sicker or healthier than those enrolled in studies.

Dr. Terry Shaneyfelt describes why blinding is important and the most commonly used methods to blind in an RCT.

This episode is part of Healthcare Triage’s series on Improving Reproducibility in Research.

Dr. Terry Shaneyfelt  describes the imporrtance of concealed allocation in a randomized controlled trial. Concealed allocation is different from blinding.

Dr. Terry Shaneyfelt explains the utility of the Intention to treat analysis.

What are the differences between Per Protocol, As Treated, and Intention to Treat?

Key Concepts in Prognostic Studies

Dr. Terry Shaneyfelt provides an overview of study designs used to glean prognostic information.

Learn About Study Designs

Dr Jack Bowden provides a brief overview of a meta-analysis. What is it, and how it helps scientists to assess and combine evidence from many different studies.

There are several types of review articles that you may encounter.  Dr. Terry Shaneyfelt describes the diffrence between a traditional, narrative review versus a Systematic Review.

Dr. Terry Shaneyfelt provides an overview of cohort study design and their strengths and limitations.

Case-control studies are observational studies that have the greatest risk of bias.  Dr. Terry Shaneyfelt describes the basic design of case-control studies and discuss their strengths and weaknesses.

Faculty from the Harvard School of Public Health describes a case report.  The video is intended to start at 1:40.  Other studies are described in this lecture following the section on case reports.

Learn About Observational Research Methods

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