Have you ever wondered how one day the media can assert that alcohol is bad for us and the next unashamedly run a story touting the benefits of daily alcohol consumption? Or how a drug that is pulled off the market for causing heart attacks ever got approved in the first place? How can average readers, who aren't medical doctors or Ph.D.s in biochemistry, tell what they should be paying attention to and what's, well, just more bullshit?Ben Goldacre has made a point of exposing quack doctors and nutritionists, bogus credentialing programs, and biased scientific studies. He has also taken the media to task for its willingness to throw facts and proof out the window. But he's not here just to tell you what's wrong. Goldacre is here to teach you how to evaluate placebo effects, double-blind studies, and sample sizes, so that you can recognize bad science when you see it. You're about to feel a whole lot better.
Now a major motion picture from HBO® starring Oprah Winfrey and Rose Byrne.Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer who worked the same land as her slave ancestors, yet her cells-taken without her knowledge-became one of the most important tools in medicine. The first'immortal'human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they'd weigh more than 50 million metric tons-as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb's effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions.Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.Now Rebecca Skloot takes us on an extraordinary journey, from the'colored'ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta's small, dying hometown of Clover, Virginia-a land of wooden slave quarters, faith healings, and voodoo-to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells.Henrietta's family did not learn of her'immortality'until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family-past and present-is inextricably connected to the dark history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of.Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family-especially Henrietta's daughter Deborah, who was devastated to learn about her mother's cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn't her children afford health insurance?Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.
From an award-winning Fortune reporter, an explosive narrative investigation of the generic drug boom that reveals the life-threatening dangers posed by globalization--The Jungle for pharmaceuticalsThe widespread use of generic drugs has been hailed as one of the most important public health developments of the twentieth century. Today, almost 90 percent of our pharmaceutical market is comprised of generics, the majority of which are manufactured overseas. We have been reassured by our pharmacists, our doctors, and our regulators that the generic and brand-name drugs are identical, generics just cheaper. But is this really true? Katherine Eban's Bottle of Lies exposes the widespread deceit behind generic drug manufacturing--creating terrifying risks for global health. Drawing on exclusive accounts from whistleblowers, inspectors, and regulators, as well as thousands of pages of confidential internal FDA documents, Eban reveals an industry where fraud is rampant, companies falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit. Meanwhile, patients unwittingly consume adulterated medicine with unpredictable and even life-threatening effects. The story of generic drugs is truly global: it connects middle America to sub-Saharan Africa, China, India, and Brazil, and encompasses every market banking on the promise of a low-cost cure. Given that tens of millions of patients take drugs of dubious quality approved with fake data, the generics industry is the ultimate litmus test of globalization: what is the risk of moving drug manufacturing offshore, and is it worth the savings? An investigation with international sweep, exotic settings, molecular mayhem, and big money at its core, Bottle of Lies reveals how the world's greatest public-health innovation has become one of its most astonishing swindles.
We're all getting older, all the time, but too often our culture defines the aging process negatively instead of embracing it as a natural part of life. Nowhere is this problem more pronounced than in our health care system, where ageist medicine often serves to worsen our medical issues instead of helping us figure out how to address or avoid them. Whether we're forty or eighty, what we need is an insider's guide to staying healthy, including choosing the right doctor, learning to play a role in managing our own care, and figuring out how to plan financially for our own future or a parent's.In this book, renowned geriatrician Mark Lachs takes listeners on a grand tour of adult medicine, showing how we can navigate a complex and confusing system so as to make the best choices for ourselves and our loved ones. With gentle humor and great wisdom, Lachs explains how being proactive and making smart decisions about health care can lay the groundwork for a satisfying, active lifestyle that lasts well into the golden years. You'll find out:-How to identify a great primary care doctor, specialist, or care facility-Why the hospital is no place for sick people-How to make home improvements that will keep the nursing home at bay-Why small life changes in your forties can lead to extra decades of good health later on
Atomic Habits will reshape the way you think about progress and success, and give you the tools and strategies you need to transform your habits--whether you are a team looking to win a championship, an organization hoping to redefine an industry, or simply an individual who wishes to quit smoking, lose weight, reduce stress, or achieve any other goal.A leading expert on habit formation reveals practical strategies to form good habits, break bad ones, and master the tiny behaviors that lead to remarkable results.
From #1 New York Times bestselling author Stephen King, the most riveting and unforgettable story of kids confronting evil since It. In the middle of the night, in a house on a quiet street in suburban Minneapolis, intruders silently murder Luke Ellis's parents and load him into a black SUV. The operation takes less than two minutes. Luke will wake up at The Institute, in a room that looks just like his own, except there's no window. And outside his door are other doors, behind which are other kids with special talents--telekinesis and telepathy--who got to this place the same way Luke did: Kalisha, Nick, George, Iris, and ten-year-old Avery Dixon. They are all in Front Half. Others, Luke learns, graduated to Back Half, "like the roach motel," Kalisha says. "You check in, but you don't check out." In this most sinister of institutions, the director, Mrs. Sigsby, and her staff are ruthlessly dedicated to extracting from these children the force of their extranormal gifts. There are no scruples here. If you go along, you get tokens for the vending machines. If you don't, punishment is brutal. As each new victim disappears to Back Half, Luke becomes more and more desperate to get out and get help. But no one has ever escaped from the Institute. As psychically terrifying as Firestarter, and with the spectacular kid power of It, The Institute is Stephen King's gut-wrenchingly dramatic story of good vs. evil in a world where the good guys don't always win.